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Capsulated Systems, Inc (CSI), which was originally incorporated in  Ohio in 1973, is now a New  York Corporation, headquartered in Ithaca,  New York at the Cornell Business and Technology Park with its manufacturing plant  is in Miamisburg, OH. CSI is a worldwide leader in the research, development, and manufacturing of Polymeric Microencapsulation systems. The company specializes in microencapsulating both inorganic and organic materials often using wall materials that are patented by CSI. These capsules can be delivered in either dry isolated microcapsule or slurry form in sizes ranging from 5 - 500 microns in diameter.


MICROENCAPSULATION


Microencapsulation began as an "art" that evolved from polymer chemistry research as a result of an identified commercial need for controlled release technology. Microencapsulation encloses a solid, liquid, or gaseous material inside a tiny "bubble" of capsule wall and holds it for a specified time or in a specific environment. Regulation of clinical composition of the capsule wall and processing techniques determines how, when or whether the "payload" inside the capsule is released.


Several different capsule technologies presently are practiced. These are: a) gelatin, starch and similar encapsulation techniques used in pharmaceuticals and foods; urea formaldehyde microencapsulation used in carbonless copy paper; c) sulfur encapsulation used in fertilizers; and d) polymeric microencapsulation.


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HOW IS CSI'S TECHNOLOGY SPECIAL?


Polymeric microencapsulation, as practiced at CSI, is a distinctive technology, delivering the most important capsule characteristics:


  • Stability (tendency to retain all the payload if desired);
  • Impermeability (resistance to moisture, air or contaminant penetration);
  • Release Performance (predisposition to release capsule contents in presence of   predesignated trigger mechanism (e.g. heat, pressure, chemical reaction, UV radiation enzymatic reaction) or at a specified time);
  • Phase Ratio (the ratio of weight of payload to total weight of capsule);
  • Uniformity (capsule size conformity as required by end-use); and
  • Environmental Safety (lack of toxicity).


    CSI's microcapsules have shown excellent results in laboratory tests for stability in extremes of temperature and humidity. The polymeric capsule wall is not susceptible to corrosion or organic breakdown. CSI's capsules can hold materials with water or oil bases, high or low pH factors and any degree of viscosity. They can safely hold toxic or volatile materials. The encapsulated material remains stable because of the innocuous nature of the capsule wall and the protection it provides from exposure to air, water, organics and other contaminants. A most important characteristic is the isolatable nature of the great majority of CSI's systems.


    MICROCAPSULE DESIGN CONSIDERATIONS


    INTERNAL PHASE MATERIALS
    RELEASE FACTORS
    - Solids
    - Time
    - Liquids
    - Pressure
    - Gases
    - Temperature
    - UV Radiation
    WALL VARIABLES
    - Chemical Reaction
    - Size
    - Bacterial Activity
    - Permeability
    - Enzymatic Reaction
    - Wettability
    - EB Radiation
    - Density
    - Film Forming Material